Question: What are the good tools for mRNA codon usage optimization and secondary structure prediction?
0
gravatar for jack
4.3 years ago by
jack790
Germany
jack790 wrote:

Hi all,

 

I'm looking for tool to do codon usage optimization for mRNAs and secondary structure prediction;

Basically I need to optimize codon usage to increase expression of the gene in host cell. Also I need to confirm that in the new sequence ribosome binding site are exposed and it's not involved in any secondary structure.

Would someone recommend some tools ?

bioinformatics genomicas • 1.5k views
ADD COMMENTlink modified 4.3 years ago by Asaf6.5k • written 4.3 years ago by jack790
0
gravatar for Asaf
4.3 years ago by
Asaf6.5k
Israel
Asaf6.5k wrote:

You can use RNAup for your second task, it gives an accessibility value for each window. 

ADD COMMENTlink written 4.3 years ago by Asaf6.5k
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