hello everyone,
i have finished differential expression analysis of my RNAseq data and retrieve the transcripts of transcription factors(TF) from differentially expressed unigenes and non differentially expressed unigenes. then i have categorized those TFs to different TF families. then i realized there are many TFs sequences which blong to the same TF family overly expressed than some other TF families, some parts of my data:

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and i wanna find overly expressed TF families in my DE TF sets at treated condition. i saw a several papers analysed this kind of data and they used fisher's exact test for that. i searched some materials about fisher's exact test, but in those example fisher's test used for 2x2 contingency table. here i still have no idea how to use fisher's test to my data. so could anyone explain to me how could i do this?