How to integrate the various blastx outputs generated by different database?

Question

[sohra]

Dear friends,

I have done blastx of a transcriptome assembly against different database, like Uniprot, refseq, nr, and now would like to integrate the several outputs as a single and non-redundant output. Of course, some hits are common among databases, but some of hits that specified as unknown protein in one database, turned to be known in another one, which I obviously want to have known protein in the final (integrated) output. I would be highly appreciated for your help to this end.

Thanks

Answer 1

[Istvan Albert]

Take the unknown proteins and align them against the known ones to resolve the ambiguities.