Assigning score/values to a group based on its elements
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Entering edit mode
7.2 years ago
muralinmars ▴ 100

I have three groups (group-A,group-B and group-C), each group contains elements with score/value for each element.

For instance

Group-A
ele-1 3
ele-2 4
ele-3 2

Group-B
ele-4 2
ele-5 7
ele-6 3

Group-C
ele-7 5
ele-8 8
ele-9 1

Now based on the element value of each group, I would like to assign value for the groups. Can I average the element value (my only concern is that in the original dataset the values are p-values). Because in the original dataset: group represents TRAIT, elements -> SNPs, and values represents score/pvalue for association signal of the SNP with a epigenome mark (histone modifications from chip-seq data).

Thanks for any suggestion

murali

biostat ChIP-Seq • 1.4k views
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2
Entering edit mode

Without more explicit information it's difficult give you any good advice. As a general rule, averaging p-values won't be useful. There are ways of aggregating them, but with more details I suspect you'll find that there are superior ways to proceed.

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