Assigning score/values to a group based on its elements
0
0
Entering edit mode
8.6 years ago
muralinmars ▴ 100

I have three groups (group-A,group-B and group-C), each group contains elements with score/value for each element.

For instance

Group-A
ele-1 3
ele-2 4
ele-3 2

Group-B
ele-4 2
ele-5 7
ele-6 3

Group-C
ele-7 5
ele-8 8
ele-9 1

Now based on the element value of each group, I would like to assign value for the groups. Can I average the element value (my only concern is that in the original dataset the values are p-values). Because in the original dataset: group represents TRAIT, elements -> SNPs, and values represents score/pvalue for association signal of the SNP with a epigenome mark (histone modifications from chip-seq data).

Thanks for any suggestion

murali

biostat ChIP-Seq • 1.6k views
ADD COMMENT
2
Entering edit mode

Without more explicit information it's difficult give you any good advice. As a general rule, averaging p-values won't be useful. There are ways of aggregating them, but with more details I suspect you'll find that there are superior ways to proceed.

ADD REPLY

Login before adding your answer.

Traffic: 2022 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6