convert SNP calls to amino acid change
2
2
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6.0 years ago
Ming Tang ★ 2.7k

I am wondering if I have a maf file describing the snps, how can I easily convert it to amino acid changes.

 " Missense_Mutation    23    66937331    66937331    T    A" ---------->  L729I  

I know I can grab the sequences around the mutation point (also needs to know where is the start codon),

and use the triplets table to find it out the changes.

I just want to know if there is an existing tool for that.

Thanks,

Ming 

 

 

snp amino acid • 5.2k views
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5
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6.0 years ago

Round about way is to

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Thanks for the link!

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6.0 years ago
Ming Tang ★ 2.7k

It looks like VEP can do this job... http://useast.ensembl.org/info/docs/tools/vep/vep_formats.html?redirect=no

Ming

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