Question: WGCNA module membership cutoff
0
gravatar for nazaninhoseinkhan
5.3 years ago by
Iran, Islamic Republic Of
nazaninhoseinkhan410 wrote:

Dear all,

It is my first time to work with WGCNA to investigate and compare co-expression networks of two organisms. 

I want to use a cutoff to select genes with higher module-membership values. When I choose 0.8 or 0.7 as cutoff, I can only find very few biological meaningful genes in each module, but when I choose 0.6 the results are more satisfactory.

My question is: is there any criteria or limit for selecting module membership values?

is 0.6 very low cutoff for module membership values?

I will appreciate any advice

Regards

Nazanin

ADD COMMENTlink written 5.3 years ago by nazaninhoseinkhan410

What "cuttoff" are you talking about? do you mean he "kWithin" value returned by the intramodularConnectivity function?

ADD REPLYlink written 5.3 years ago by informatics bot640
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