I work with amino-acid networks. Basically, I want to compare a network of a wild-type protein to the network of the same protein mutated in one position. The thing is, I want to do this for every (single) mutation possible. Therefore, if the sequence of my protein is of length N, I first need to produce the N*19 mutated proteins first. The network is defined by atomic distances so I need a structure for every mutation and I'm doing it in Silico. I know FoldX is not time consuming, both in terms of time it takes to produce the mutations and in terms of telling it what mutations I want (I only need a list of mutations).
I would like to know if there are other softwares than can do the same think as FoldX, that are time acceptable to produce many mutations, in my case 1577 mutations.