I have some concerns in the terms of the "random seed" parameter which one can set in Comparative Marker Selection at Gene Pattern. Firstly, I understand that this is the parameter related to the random number generating to produce the permutations. However, I do not understand how it works.
I. e. if one use GSEA software the "random seed" is not numerical value, but "timestamp". So, the first question is - what does mean timestamp random seed?
Second thing is, that if one performs Comparative Marker Selection the random seed is by default set to some enigmatic value like 779948241. So, the second question is - what does this value mean?
I do not understand the difference between timestamp in GSEA and 779948241 in Comparative Marker Selection. Moreover, if I i.e. change this value to 0 how does it affect my data and the results of analysis?
Unfortunately, both manuals (GSEA and Comparative Marker Selection) do not explain this parameter. Please, explain it to me or suggest any literature about that would be understandable for not statistician.
Best regards and thanks in advance for any help!