Tool For Recognize Conserved Structural Motifs Among Dna Sequences
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Entering edit mode
12.2 years ago
Anima Mundi ★ 2.9k

Hello,

I would like you to suggest me a tool capable to recognize structural conserved motifs among a MSA of DNA sequences of interest, rather than simply recognize a consensus in the nucleotide sequence.

For example, for the sequences:

1 ATTA
2 GTTG
3 CGGC

The common structure should be XYYX (X, Y are different incognite nucleotides).

Instead, for the sequences:

1 ATTA
2 ACGA
3 AGAA

The common structure should be ANNA. Hope this is clear enough.

structural-motif conservation • 2.2k views
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Entering edit mode
12.2 years ago
Hamish ★ 3.2k

Not sure if this is what you are looking for, but a tool that comes to mind for discovering motifs in a set of DNA sequences is DREME, part of the MEME suite.

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Thank you, I will try to understand how DREME works; in case I will mark this as the accepted answer ;).

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