Question: Is there a Transmembrane Topology Prediction tool in which one can specify the number of Transmembrane domains to be found ?
gravatar for mithrandir
4.1 years ago by
mithrandir40 wrote:

I want to find the Transmembrane domains in a sequence of protein. The number of transmembrane domains displayed by various tools differs. I have used TOPCONS, OCTOPUS, etc. Is there a tool in which I can force the output to give the desired number of transmembrane domains?

ADD COMMENTlink modified 4.1 years ago by Michael Dondrup47k • written 4.1 years ago by mithrandir40
gravatar for Michael Dondrup
4.1 years ago by
Bergen, Norway
Michael Dondrup47k wrote:

You could try CCTOP. It allows you to specify additional constraints, after the prediction is complete, click customize. There you can add additional custom constraints at the bottom of the page (click the Additional +), and specify the topology type and location, and recalculate.

TOPDB is a database of transmembrane proteins and annotated topology, where you can apply a search filter on the number of transmembrane domains.

ADD COMMENTlink modified 4 weeks ago by RamRS25k • written 4.1 years ago by Michael Dondrup47k
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