Question: What simulation software/softwares should I use?
gravatar for jasonchen608
4.7 years ago by
jasonchen6080 wrote:


Hello, sorry for asking this stupid question. First of all, I am an idiot in trying to find information on the web, so don't blame me if you think this question is kinda broad/hard to answer. I am doing an in silico simulation of an oncolytic cancer therapy, but I cannot find a software that suits my needs. I am an independent researcher -not affiliated with research centers or universities - and I am not experienced in software design or program writing. I hope you guys can help me.

The software should be able to simulate drug tumor penetration (the drug results in tumor growth) and its growth effects.

Do I have to use several softwares in combination to simulate this? 

Also, how do I delete questions on BioStar? 

software • 1.0k views
ADD COMMENTlink modified 4.7 years ago • written 4.7 years ago by jasonchen6080

I am sorry the way you ask this question, there is no way of answering it. You want to simulate drug tumor penetration but you do not state how or more specific what you want to simulate: distribution of a molecule in the blood stream, its mechanism, effectiveness versus tumor progression / drug evasion etc. The question is just to unspecific. Also you do not give a background or anything. Do not get me wrong but this question sounds similar to a high school student who asks for help to shoot a rocket to the moon.

I am not sure how I would proceed in your position but if you do not have any idea of how you want to achive what you want to do, there is no way of helping you. The probably best way to go for you would be to take some online courses (e.g to look into for biological simulations but some introduction into programming or computer science also would not hurt (and might be a prequesite)

ADD REPLYlink written 4.7 years ago by Aerval280

Any simulation will be only as good as the underlying model, the model selection is the core. I can only advise to read some review overview papers on tumor growth (throwing in some random results)

And you might also throw in a diffusion model:

A lot of those models might have been implemented in Matlab, that is what a lot of modelling/simulation people use.

However, I think that your problem is quite complex (and ill defined!) and would be easily good for a one to a couple of PhD theses, so it might be impractical without any experience in modelling. You might want to look for collaborators though.

ADD REPLYlink modified 9 months ago by RamRS30k • written 4.7 years ago by Michael Dondrup47k
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