Question: co-expression between transcription factors and their targets
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gravatar for nazaninhoseinkhan
3.3 years ago by
Iran, Islamic Republic Of
nazaninhoseinkhan360 wrote:

Dear all,

I have a basic question.

I have constructed gene regulatory network for a bacterial pathogen based on expression data.

In resulted network high degree of co-expression was observed between TFs and their corresponding targets.

Can I come to this conclusion that as a result of such a considerable co-expression this bacterial species can better adapt to harsh conditions and can out-compete other bacterial species in for example co-infections?

I will appreciate any explanation

Nazanin

ADD COMMENTlink modified 3.3 years ago by Devon Ryan90k • written 3.3 years ago by nazaninhoseinkhan360
1
gravatar for Devon Ryan
3.3 years ago by
Devon Ryan90k
Freiburg, Germany
Devon Ryan90k wrote:

"Can I come to this conclusion that as a result of such a considerable co-expression this bacterial species can better adapt to harsh conditions and can out-compete other bacterial species in for example co-infections?"

From that alone? No, you can't reasonably come to that conclusion.

ADD COMMENTlink written 3.3 years ago by Devon Ryan90k
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