co-expression between transcription factors and their targets
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8.2 years ago

Dear all,

I have a basic question.

I have constructed gene regulatory network for a bacterial pathogen based on expression data.

In resulted network high degree of co-expression was observed between TFs and their corresponding targets.

Can I come to this conclusion that as a result of such a considerable co-expression this bacterial species can better adapt to harsh conditions and can out-compete other bacterial species in for example co-infections?

I will appreciate any explanation

Nazanin

co-expression TFs-target genes • 1.8k views
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Entering edit mode
8.2 years ago

"Can I come to this conclusion that as a result of such a considerable co-expression this bacterial species can better adapt to harsh conditions and can out-compete other bacterial species in for example co-infections?"

From that alone? No, you can't reasonably come to that conclusion.

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