in silico study of antimicrobial peptide

Question

[Arindam Ghosh]

I have a peptide that has shown antimicrobial activity in vitro. I want to go for in silico studies to see the specific action. Will I be able to arive at a meaningful conclusion by just doing membrane dynamics of the peptide? Any other suggestions.....

Answer 1

[natasha.sernova]

See these articles:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563516/

http://www.sciencedirect.com/science/article/pii/S0196978112003221

http://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-015-1849-x

https://www.researchgate.net/publication/270397201_In_Silico_Design_of_Antimicrobial_Peptides

Lipid bilayer:

http://www.ncbi.nlm.nih.gov/pubmed/24411253

http://www.ncbi.nlm.nih.gov/pubmed/25087882

http://www.ncbi.nlm.nih.gov.sci-hub.cc/pubmed/26244728

http://www.ncbi.nlm.nih.gov/pubmed/23505359