I came to know that RNA-seq data follows bionomial/ negative bionomial distribution. Well i am not a statistician, but i studied about basics of statistics, statistical terms, probability, distributions and statistical tests on internet.The text available on internet use coin flipping, playing cards, throwing dice type of examples which helped me to understand the statistics (well i say basic statistics) behind it .but when i come to RNA-seq data i am not able to correlate and comprehend.
Can anyone explain (or provide me a link) RNA-seq data distribution (eg. bionomial / negative bionomial) and statistical (eg. T test) test taking an example of RNA-seq count/FPKM data, where we have input parameters:
1.Number of genes in organisms
2.Number of reads mapped on these genes
Thanks in Advance :)