about the genome coordinates for mutations

Question

[Bogdan]

Dear all,

please could you advise : given a protein sequence (ie TP53), that has a mutation in its aminoacid sequence (c 526T>A, p C176S), is there a quick way to retrieve the genome coordinates for the mutation in the protein sequence ?

thanks,

bogdan

[GenoMax]

This is an old biostars thread but see if the answers help: Amino Acid Change To Genomic Location

[GenoMax]

Tagging @Pierre. Pierre Lindenbaum

Is this the right location for your variation toolkit: https://github.com/lindenb/variationtoolkit

Answer 1

[Bogdan]

Thank you for the quick reply !