Does anyone know if 23andme switched to GRCh38 or they are still using GRCh37?
According to Which reference genome does 23andMe use?, it's GRCh37.
I can confirm this is currently the case by cross-referencing the coordinates in my raw 23andme data with dbSNP. (e.g. rs13096 is at coordinate 25359841, not 25206907)
Another question to clear up the confusion.. I am comparing the genotypes of rsIDs from the 23andme files versus the genotypes from snpedia.
23andme file for individual X:
on snpedia (for rs4988235):
on snpedia (for rs9939609):
after making some comparisons the results (i.e. the results i deduced):
if you noticed, in case of rs4988235 i flipped (i.e. converted) the genotype AA to TT because SNPedia shows that the orientation is minus, whereas i didn't flip the genotype for the rs9939609 because the orientation is plus.
So my question is, am I doing it the right way?
I apologize if my question is naive, my background is in computer science not genomics.
Please ask this as a new question.
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