Question: Multiple Proteome comparision
gravatar for Mehmet
2.7 years ago by
Mehmet460 wrote:

Dear All:

I have a proteome data of a non model organisms. I want to see which protein families are expanded in the proteome data compared to another related or non related species. For this:

Which procedure should I follow?

Thank you.

sequencing rna-seq genome • 715 views
ADD COMMENTlink modified 2.7 years ago by Juke-341.8k • written 2.7 years ago by Mehmet460
gravatar for Juke-34
2.7 years ago by
Juke-341.8k wrote:

Have a look to clusterisation tools such as OrthoMCL, InParanoid, OrthoDB and so one. Once the clusters built, you can analyse for each cluster the number of putative Orthologs of your species compared to the others.

ADD COMMENTlink written 2.7 years ago by Juke-341.8k


I have used orthoMCL to find ortholog proteins in 12 proteome files. I mean I want to search some protein domains in 12 proteome files, such as neuropeptides, peptides etc. to find which protein domains are expanded in my species proteome files. For this, what kind of analyses and tools should I use?

ADD REPLYlink written 2.7 years ago by Mehmet460

To add domain information to your proteins in order to compare their domain content you should launch Interproscan5.

ADD REPLYlink written 2.6 years ago by Juke-341.8k
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