Question: Are there any resources for gene expression data in patients who have melanoma?
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gravatar for goldname98
3.0 years ago by
goldname980
goldname980 wrote:

I have a training dataset from TCGA to perform survival analysis, but I would like to find another dataset for testing. Do you know of any datasets that have patients, their time until the event occurs, and their status("alive", "dead", "recurred/progressed", etc...)?

melanoma rna-seq data • 1.1k views
ADD COMMENTlink modified 3.0 years ago by Denise - Open Targets5.0k • written 3.0 years ago by goldname980
0
gravatar for Mike
3.0 years ago by
Mike1.3k
UK
Mike1.3k wrote:

have a look on GEO data series "GSE22153", 57 Melanoma sample with Different Clinical Outcome.

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE22153

ADD COMMENTlink written 3.0 years ago by Mike1.3k
0
gravatar for Denise - Open Targets
3.0 years ago by
UK, Hinxton, EMBL-EBI
Denise - Open Targets5.0k wrote:

The National Institute of Health GDC Data Portal seems to have RNASeq data for patients with skin cutaneous melanoma. You can get data per age at diagnosis among other statuses.

ADD COMMENTlink written 3.0 years ago by Denise - Open Targets5.0k

GDC SKCM data are derived from the same TCGA data, so not a good set for validation. However, for the particular scientific question, why not split the data set into 2/3 for training, and 1/3 for validation?

ADD REPLYlink written 2.8 years ago by Zhenyu Zhang240
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