Hi guys, I need to create a network of interacting proteins from MS expression measurements. Do you know which tools, softwares and algorithms are available to do this?
Thank you in advance
Don't you need interaction data, instead of expression data, in order to do this? Like yeast two hybrid for instance?
Hi. I only have protein expression data from a MS experiment.
Look at this paper:
NetworkAnalyst - integrative approaches for protein–protein interaction network analysis and visual exploration
You can use Cytoscape. Granted, you are going to first need interaction data - which proteins are already interacting with what, etc.. Then you can use your expression data as a way to weigh the strength of each interaction.
Thank you very much guys!
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