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Question: Heritability of pigmentation traits
1
gravatar for GabrielMontenegro
3.8 years ago by
GabrielMontenegro • 560
United Kingdom
GabrielMontenegro • 560 wrote:

I know that many pigmentation traits (skin, hair and eye color) are highly heritable. For instance, I assume that the heritability of eye color should be high.

I've been trying to find articles estimating heritability of these traits either based on twin studies or using more modern methods based on GWAS SNP data, for instance calculated using GCTA or LDAK, but couldn't find any.
heritability • 1.0k views
ADD COMMENT • link •
modified 3.8 years ago by Fabio Marroni • 2.6k • written 3.8 years ago by GabrielMontenegro • 560

Have you tried to search pubmed? If so you would have found this review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491390/

ADD REPLY • link written 3.8 years ago by Michael Dondrup ♦ 47k

I checked several, including that one. Maybe I am completely missing it, but I still can't find on that paper any estimate of heritability.

ADD REPLY • link written 3.8 years ago by GabrielMontenegro • 560

What do you mean by estimate? The trait is heritable, are you looking for a quantitative prediction?

ADD REPLY • link written 3.8 years ago by Michael Dondrup ♦ 47k

Yes, I was looking for the actual value. Thank you anyway.

ADD REPLY • link written 3.8 years ago by GabrielMontenegro • 560
3
gravatar for Fabio Marroni
3.8 years ago by
Fabio Marroni • 2.6k
Italy
Fabio Marroni • 2.6k wrote:

Heritability of Skin Color 1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212702/

2) https://genepi.qimr.edu.au/contents/p/staff/CV018.pdf (h2 ranging from 0.37 to 0.83)

Probably for eye color will be harder, since it is usually not quantitatively measured.
ADD COMMENT • link modified 3.8 years ago • written 3.8 years ago by Fabio Marroni • 2.6k

Great! Thanks for this! If you come up with a study using GWAS SNP data please let me know :)

ADD REPLY • link written 3.8 years ago by GabrielMontenegro • 560
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