Question: Heritability of pigmentation traits
1
gravatar for GabrielMontenegro
2.3 years ago by
United Kingdom
GabrielMontenegro500 wrote:

I know that many pigmentation traits (skin, hair and eye color) are highly heritable. For instance, I assume that the heritability of eye color should be high.

I've been trying to find articles estimating heritability of these traits either based on twin studies or using more modern methods based on GWAS SNP data, for instance calculated using GCTA or LDAK, but couldn't find any.

heritability • 752 views
ADD COMMENTlink modified 2.3 years ago by Fabio Marroni2.1k • written 2.3 years ago by GabrielMontenegro500

Have you tried to search pubmed? If so you would have found this review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491390/

ADD REPLYlink written 2.3 years ago by Michael Dondrup45k

I checked several, including that one. Maybe I am completely missing it, but I still can't find on that paper any estimate of heritability.

ADD REPLYlink written 2.3 years ago by GabrielMontenegro500

What do you mean by estimate? The trait is heritable, are you looking for a quantitative prediction?

ADD REPLYlink written 2.3 years ago by Michael Dondrup45k

Yes, I was looking for the actual value. Thank you anyway.

ADD REPLYlink written 2.3 years ago by GabrielMontenegro500
3
gravatar for Fabio Marroni
2.3 years ago by
Fabio Marroni2.1k
Italy
Fabio Marroni2.1k wrote:

Heritability of Skin Color 1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212702/

2) https://genepi.qimr.edu.au/contents/p/staff/CV018.pdf (h2 ranging from 0.37 to 0.83)

Probably for eye color will be harder, since it is usually not quantitatively measured.

ADD COMMENTlink modified 2.3 years ago • written 2.3 years ago by Fabio Marroni2.1k

Great! Thanks for this! If you come up with a study using GWAS SNP data please let me know :)

ADD REPLYlink written 2.3 years ago by GabrielMontenegro500
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