Question: Differences between co-expression and co-regulation
0
gravatar for debitboro
3.2 years ago by
debitboro160
Belgium
debitboro160 wrote:

Hi biostars community,

What's the difference between co-expression and co-regulation, is there any relationship between these two notions ?

co-regulation co-expression • 5.3k views
ADD COMMENTlink modified 3.2 years ago by Ron990 • written 3.2 years ago by debitboro160

As stated this is not a bioinformatics question :)

ADD REPLYlink modified 3.2 years ago • written 3.2 years ago by genomax77k
4
gravatar for WouterDeCoster
3.2 years ago by
Belgium
WouterDeCoster42k wrote:

In my opinion, co-regulation is the fact that two transcripts (or more) are regulated by the same mechanism, e.g. the same transcription factor. Therefore, they show co-expression, their expression is correlated.

But you can also observe co-expression without knowing for sure those genes are co-regulated. Co-expression suggests co-regulation.

ADD COMMENTlink written 3.2 years ago by WouterDeCoster42k
2
gravatar for harold.smith.tarheel
3.2 years ago by
United States
harold.smith.tarheel4.5k wrote:

To expand on @WouterDeCoster's answer, co-expression describes the phenomenon while co-regulation describes the mechanism.

ADD COMMENTlink written 3.2 years ago by harold.smith.tarheel4.5k
1
gravatar for Ron
3.2 years ago by
Ron990
United States
Ron990 wrote:

Nice little review on this topic:

http://infolab.stanford.edu/~wangz/project/genome/G2004.2/zhang.pdf

ADD COMMENTlink written 3.2 years ago by Ron990
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