Question: Which yeast genes would have the most similar gene expression pattern?
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gravatar for tfhahn
2.3 years ago by
tfhahn50
tfhahn50 wrote:

I would like to test my model. Therefore, I would need to know where I can find a list of yeast genes, which can be sorted based on their similarities in their expression pattern. Where could I find such a list or how could I generate it?

ADD COMMENTlink modified 2.3 years ago by theobroma221.1k • written 2.3 years ago by tfhahn50

Which yeast genes would have the most similar gene expression pattern?

The genes associated with ribosome biogenesis are described as being tighly co-regulated "to ensure that the components of the ribosome are available in equimolar amounts". The economics of ribosome biosynthesis in yeast.

ADD REPLYlink written 2.3 years ago by Carlo Yague4.5k
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gravatar for Jean-Karim Heriche
2.3 years ago by
EMBL Heidelberg, Germany
Jean-Karim Heriche19k wrote:

You can get yeast gene expression datasets from public repositories such as ArrayExpress. SGD' SPELL resource has integrated expression data which may be closer to what you want.

ADD COMMENTlink written 2.3 years ago by Jean-Karim Heriche19k
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gravatar for theobroma22
2.3 years ago by
theobroma221.1k
theobroma221.1k wrote:

You could just simulate it and make a synthetic dataset by using a certain distribution, like any random or beta distribution with a pre-determine mean and variance.

ADD COMMENTlink written 2.3 years ago by theobroma221.1k
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