Question: Criteria for denoting unknown data in cosmic db
gravatar for Peavil
2.9 years ago by
Peavil10 wrote:

I am wondering the criteria for denoting unknown data in cosmic db.

for example PIK3CA gene,

Accession Number    Gene CDS length HGNC ID Sample name ID_sample   ID_tumour   Primary site    Site subtype 1  Site subtype 2  Site subtype 3  Primary histology   Histology subtype 1 Histology subtype 2 Histology subtype 3 Genome-wide screen  Mutation ID Mutation CDS    Mutation AA Mutation Description

NM_006218.1 3207    8975    2493513 2493513 2356117 breast  NS  NS  NS  carcinoma   NS  NS  NS  n   COSM29325   c.? p.H1047R

NM_006218.1 3207    8975    1670204 1670204 1583490 breast  NS  NS  NS  carcinoma   NS  NS  NS  n   COSM775 c.3140A>G   p.H1047R    Substitution - Missense

These two data seem to be similar. Even Mutation AA (Amino acid) has the same value(p.H1047R), the below data has the cds number(c.3140A>G), and the above data shows that the cds number is unknown(c.?).

I wonder why I know the "mutation AA information" but the cds information is unknown.

cancer cosmic database cosmic • 762 views
ADD COMMENTlink modified 2.9 years ago by WouterDeCoster43k • written 2.9 years ago by Peavil10
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1467 users visited in the last hour