Question: PPI data network
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gravatar for miglanivarnika.26
4 months ago by
miglanivarnika.2610 wrote:

Hi! I want to build a PPI network by union of three PPI databases. How should I do that, Is there an online tool to do so? If yes then which one and how to do the above stated task. Thank you in advance. Please help me.

gene genome • 218 views
ADD COMMENTlink modified 4 months ago • written 4 months ago by miglanivarnika.2610
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gravatar for Jean-Karim Heriche
4 months ago by
EMBL Heidelberg, Germany
Jean-Karim Heriche13k wrote:

You could use iRefIndex. It integrates data from several protein-protein interaction databases. The last update was two years ago though. If you need to do it yourself, you need to map all interaction partners to the same reference gene or protein set. I typically map all interaction partners to EnsEMBL genes because I usually need gene level interactions and also this is easier than trying to identify protein isoforms across databases. If the latter is what you want, look at the method in the iRefIndex paper.

ADD COMMENTlink written 4 months ago by Jean-Karim Heriche13k
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gravatar for miglanivarnika.26
4 months ago by
miglanivarnika.2610 wrote:

Ok, Thank you, This was really helpful

ADD COMMENTlink written 4 months ago by miglanivarnika.2610
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