Question

Cufflinks analysis of Tophat BAM file

0

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6.6 years ago

qudrat ▴ 100

When I split BAM file by chromosome and then Cufflinks by chromosome-wise takes very less time compared to Cufflinks on whole BAM file. Can somebody help me explain this?

RNA-Seq alignment • 1.3k views

ADD COMMENT • link updated 6.6 years ago by Kevin Blighe 87k • written 6.6 years ago by qudrat ▴ 100

score 2 · Accepted Answer · 2017-09-25

2

Entering edit mode

6.6 years ago

Kevin Blighe 87k

Your RAM and I/O are being used more efficiently when you split the file.

ADD COMMENT • link 6.6 years ago by Kevin Blighe 87k