sciClone input LOH
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3.8 years ago

Dear all,

I want to use sciclone on my somatic variant data. I am confused about the input it takes. One is the CNA information but incase of LOH input file, Is it cnLOH or LOH ? what i mean is looking at the results from ASCAT, should i give regions where we have major 2n and monir 0, or all the regions where the minor is 0 with major allele could be 2n, 3n trisomies, so on etc...

Can anyone explain what LOH files mean here in context of sciclone input?

Thanks in advance.

sciclone input LOH • 1.5k views
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perhaps, this may be the answer to what i was looking.. which i missed earlier The meaning of VAF and LOH in sciclone

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Yep, that's the definition you're looking for. Hope it cleared things up!

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