Question: sciClone input LOH
gravatar for shumaila.sayyab
23 days ago by
shumaila.sayyab0 wrote:

Dear all,

I want to use sciclone on my somatic variant data. I am confused about the input it takes. One is the CNA information but incase of LOH input file, Is it cnLOH or LOH ? what i mean is looking at the results from ASCAT, should i give regions where we have major 2n and monir 0, or all the regions where the minor is 0 with major allele could be 2n, 3n trisomies, so on etc...

Can anyone explain what LOH files mean here in context of sciclone input?

Thanks in advance.

input sciclone loh • 111 views
ADD COMMENTlink written 23 days ago by shumaila.sayyab0

perhaps, this may be the answer to what i was looking.. which i missed earlier The meaning of VAF and LOH in sciclone

ADD REPLYlink written 21 days ago by shumaila.sayyab0

Yep, that's the definition you're looking for. Hope it cleared things up!

ADD REPLYlink written 21 days ago by Chris Miller18k
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