Question: Are there any tools to simulate mutations?
gravatar for MAPK
2.1 years ago by
United States
MAPK1.5k wrote:

I am working on a gene mutation method. I am trying to test my tool using 1000 genome vcf file (multigenome vcf file). I am using only one chromosome(as that should be enough to test my algorithm). I now want to simulate mutations in ~10 samples of 1K genome project vcf file. Can someone please suggest me a tool that can be used to simulate mutation in a multgenome vcf file?

mutation vcf • 1.0k views
ADD COMMENTlink modified 2.1 years ago by Gabriel R.2.6k • written 2.1 years ago by MAPK1.5k
gravatar for Gabriel R.
2.1 years ago by
Gabriel R.2.6k
Danmarks Tekniske Universitet
Gabriel R.2.6k wrote:

msprime ( You can simulate a demography of say 10 individuals and output segregating sites as VCF. You can even plug in a recombination map.

ADD COMMENTlink written 2.1 years ago by Gabriel R.2.6k
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