Entering edit mode
6.5 years ago
Shicheng Guo
★
9.4k
List for Genetic Background Outlier Remove Programme
Anyone compared these two tools before? EIGENSTRAT vs mdsoutlier
Which one is better? What's the difference between the results?
First: EIGENSTRAT
https://github.com/Shicheng-Guo/EIG/tree/master/EIGENSTRAT
Second: mdsoutlier
Your links were broken, which is probably why nobody responded for more than a week. I have just fixed them.
My general rule of thumb is >3 standard deviations and it's an outlier. Outlier detection is not and should never be an exact science, though. There are many situations in which an outlier can be due to genuine biological reasons, meaning that by eliminating it you'd be throwing away an interesting sample.
If EIGENSTRAT and mdsoutlier both have publications behind them, then you can easily justify the use of either.