Question: SNP statistical analysis
0
gravatar for arash.iranzadeh1980
17 months ago by
arash.iranzadeh198010 wrote:

Hi, I am doing a genome wide association study on a series of SNPs. I have confronted many statistical tests like logistic regression, fisher exact test, association test, Chi square etc. Is there any good reference or reading materials for studying these tests on SNPs. I need examples with numerical values to understand how to interpret the final results.

snp statistical analysis • 922 views
ADD COMMENTlink modified 17 months ago by AlexRT10 • written 17 months ago by arash.iranzadeh198010
1
gravatar for Kevin Blighe
17 months ago by
Kevin Blighe41k
Guy's Hospital, London
Kevin Blighe41k wrote:

My recommendation to you would be to start looking through the PLINK documentation, which is very comprehensive and provides explanations on the majority of statistical tests used in the realm of GWAS.

The documentation can be found here: http://zzz.bwh.harvard.edu/plink/

If you want to elaborate more on a specific analysis, search via a search engine.

Kevin

ADD COMMENTlink written 17 months ago by Kevin Blighe41k
1
gravatar for AlexRT
17 months ago by
AlexRT10
Canada
AlexRT10 wrote:

A couple of interesting reads on GWAS and SNPs, complementing PLINK documentation:

https://www.nature.com/articles/nprot.2010.116 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154648/ https://www.frontiersin.org/articles/10.3389/fgene.2015.00149/full

Alex

ADD COMMENTlink written 17 months ago by AlexRT10
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