Question: RNA-Seq and WGS analysis applied in genes expression
gravatar for bwczech
10 weeks ago by
bwczech0 wrote:


I need to find some publications about an analysis of the diversity of gene expression based on WGS and RNA-Seq.

I would like to sequent the genome and the transtripts (a sample of liver tissue and muscle tissue) in three individuals of pig. I would like to explain differences in expression using non-coding DNA sequences. Research will be based on WGS and RNA-Seq. Do you know articles about similar issues? Or any other proposition how to use a WGS and RNA-Seq together to do research about expression analysis?

rna-seq expression wgs gene • 165 views
ADD COMMENTlink written 10 weeks ago by bwczech0

Any idea? How to analyse Gene Expression based on RNA and DNA sequences together?

ADD REPLYlink written 10 weeks ago by bwczech0

I am not aware of any major study that has analysed these data types together. You may have to do some form of a manual screen over your results and then focus on the regions of interest. For example, one method would be to see how mRNA transcription alters between a reference and variant allele at a specific locus.

ADD REPLYlink written 9 weeks ago by Kevin Blighe12k
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