Question: Filtering using TLOD score in MuTect2?
gravatar for Sharon
13 months ago by
Sharon420 wrote:

Hi Every one

I have more than 40 K somatic mutation per tumor sample we have. I think we have lots of false positives because we used a panel of normal (10 samples) but we don't have a matched normal-tumor that help filtering germline better.

Would being very stringent in the TLOD score a reasonable filtering step?


ADD COMMENTlink written 13 months ago by Sharon420
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1133 users visited in the last hour