Tool: HEXplorer: Scanning splice site sequence surroundings for splice enhancing/repressing properties
0
gravatar for caggtaagtat
9 months ago by
caggtaagtat380
caggtaagtat380 wrote:

Hi everbody,

I would like to shortly introduce to you the tool my working group developed, the HEXplorer.

  • Helps you to check the sequence surrounding around 5' splice sites for splice enhancing or repressing Splice Regulatory Elements (SREs) nearby.

  • Visualizes the effect of point mutations on the SRP binding properties of a given genomic sequences

  • Calculates intrinsic strength of possible splice donors or acceptors (HBS and maxent score)

  • Validated through various point mutation analysis

You can find some background for the program in this paper.

ADD COMMENTlink modified 9 months ago • written 9 months ago by caggtaagtat380
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1954 users visited in the last hour