Question: Sample size to identify RNA editing sites
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weiwei08 • 0 wrote:
Good day all.
I am freshie in the field of research and recently starting my study in identifying RNA editing sites in my sample by comparing RNA and DNA sequencing data collecting from a single individual. While there were few published that identify RNA editing sites from only single individual (n=1) as well as include multiple individuals, i would like to seek advise from all of you on:
1) Is n=1 sufficient to identify RNA editing sites?
2) How does my sample size affect the edited sites discovered?
3) How do researchers usually justify for their sample size in writing a paper?
Thank you so much in advance!
