Question: What is unigene
gravatar for athira112athira
11 days ago by
athira112athira0 wrote:

I do not understand precisely what is a unigene? I've been looking on the internet but I always find UniGene NCBI database as a result. Does anyone know the definition of what is a unigene?

rna-seq gene • 69 views
ADD COMMENTlink modified 11 days ago by lieven.sterck940 • written 11 days ago by athira112athira0
gravatar for lieven.sterck
11 days ago by
Belgium, Ghent, VIB
lieven.sterck940 wrote:

In the most strict way (biological) a unigene is a unique transcript that is transcribed from a genome. So that should corresponds to an isoform (or gene if there are no isoforms).

however, in (transcript) assembly context people often refer to a unigene as a uniquely assembled transcript which not necessarily corresponds to the biological interpretation (== due to artifacts you could end up with several assembled transcripts for the same biological unigene)

ADD COMMENTlink written 11 days ago by lieven.sterck940
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