Hello! I am comparing the transcriptomes of 3 types of cells, I'll call them A1, A2 and B for convenience. What would be the best way to see the relationship between the transcriptomes (i.e which 2 populations have the most variance and which 2 populations have the least variance and so on)? I did the PCA analysis and all replicates related to each of the samples cluster together and PC1 (44%) shows more variance between A1 and B, while PC2 (26%) shows some variance between A1 and A2 but it is difficult to make any inferences if the transcriptomes of A1 and A2 have more similarities or A1 and B have more similarities. I wanted to do a venn diagram but wasn't sure how to approach this, since there's no control/stem cell population to compare A1, A2, B. If anyone has any suggestions that would be much appreciated.