Fst and pairwise Fst

Question

[debaratichakraborty31]

What is the difference between Fst and pairwise Fst? How to calculate it in GenoDive?

[h.mon]

Hello debaratichakraborty31!

We believe that this post does not fit the main topic of this site.

Not a bioinformatics question (What is the difference between Fst and pairwise Fst?) and not enough information provided (How to calculate it in GenoDive?).

For this reason we have closed your question. This allows us to keep the site focused on the topics that the community can help with.

If you disagree please tell us why in a reply below, we'll be happy to talk about it.

Cheers!

[h.mon]

Hi debaratichakraborty31,

I reopened your question, but please take some time to improve it. As it stands now, it is poorly formulated and it is unlikely you will get any help. Please read How To Ask Good Questions On Technical And Scientific Forums for hints.

[debaratichakraborty31]

I have already solved the problem. Anyways thanks for the help.

Answer 1

[grant.hovhannisyan]

When calculated within one population, Fst is a measure of average pairwise distances between pairs of individuals (haplotypes) in terms of allele frequencies. For between population comparisons Fst is more intuitive and basically is a "difference" between allele frequencies of two populations. It is a very fundamental measure, so you can have a look even in Wikipedia page https://en.wikipedia.org/wiki/Fixation_index and go further by references for mathematical details.