I want to make a consensus genome by replacing variants. I want to replace homozygous variants in the reference. Is it right to replace the heterozygous variants? The ALT allele must correspond to the homozygous chromosome of a diploid organism. That's my understanding. So I am thinking of not replacing such variants.
Question: Should I replace heterozygous variants to make a consensus
4 months ago by
deepti1rao • 20
deepti1rao • 20 wrote:
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