Question: How do we call this phenomenon in evolution?
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gravatar for johnnytam100
12 months ago by
johnnytam100100
johnnytam100100 wrote:

I have a protein of interest, which is conserved from bacteria, archaea to eukaryotes.

After aligning the sequence a highly conserved domain of the homologs, I have divided the sequences into three groups which differ by a significant number of the aligned position that shared a common trend, in terms of the percentage of the amino acid composition at the respective position, for illustration:

For aligned residue position 1,

group 1 : 100% lysine

group 2 : 50% lysine, 50% arginine

group 3 : 100% arginine

Interestingly, for some positions the mutation is less conservative, for example:

group 1 : 100% histidine

group 2 : 50% histidine, 50% aspartate

group 3 : 100% aspartate

Does anyone know how do we call such a phenomenon in evolution?

Thank you.

evolution • 294 views
ADD COMMENTlink modified 12 months ago • written 12 months ago by johnnytam100100

Conservative, semiconservative, and radical substitution/replacement?

https://en.wikipedia.org/wiki/Conservative_replacement

ADD REPLYlink written 12 months ago by rbagnall1.4k

Yes, that's much related. I have just read from a reference book, "co-evolving residues". Please throw in more specific terms or examples describing such a phenomenon if anyone has.

ADD REPLYlink written 12 months ago by johnnytam100100

Natural selection :p

ADD REPLYlink written 12 months ago by 5heikki8.6k
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