Question: Pearson's Correlation Coefficient and expression matrix
0
gravatar for Morteza Hadizadeh
12 months ago by
Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
Morteza Hadizadeh20 wrote:

Hi every one,

I have an expression matrix, the rows contain 550 mutual DEGs and columns contain 73 samples (550*73), samples are divided into 2 groups (control and case), 30 sample for control and 43 samples for the case. I want to calculate Pearson's Correlation Coefficient for each group to construct a co-expression network.

I would be grateful if you could guide me to do it.

R • 1.1k views
ADD COMMENTlink modified 12 months ago by biobiu110 • written 12 months ago by Morteza Hadizadeh20

What about MDS? I think that to your purpose it would be more illustrative/explanative..

ADD REPLYlink written 12 months ago by Buffo1.8k

Mutual differential expression genes contain up and down-regulated genes.

ADD REPLYlink written 12 months ago by Morteza Hadizadeh20
2
gravatar for biobiu
12 months ago by
biobiu110
United States
biobiu110 wrote:

Use the function cor in R. You have a good example here.

ADD COMMENTlink written 12 months ago by biobiu110

Thank you so much for your guidance.

ADD REPLYlink written 12 months ago by Morteza Hadizadeh20
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