Course: Approaches and Computational tools for CRISPR Genome editing
Where: Free University of Berlin (Germany)
When: 28-30 October 2019
1) Dr. Luca Pinello (http://pinellolab.org/; Harvard Medical School, USA)
2) Dr. Kendell Clement (http://pinellolab.org/; Harvard Medical School, USA)
Clustered regularly interspaced short palindromic repeats (CRISPR) genome editing has revolutionized the ability to modify a genome of interest in a targeted and programmable way. This system has accelerated biological discovery and clinical treatments and new genome editing variants with different editing properties are being introduced at a rapid pace. A variety of computational tools have been developed to address key challenges in the design and analysis of genome editing experiments. In this course we will introduce common design and analysis strategies, as well as state-of-the-art methods and tools that attendees can use to address their own genome editing needs.
TARGETED AUDIENCE & ASSUMED BACKGROUND
This course is aimed at researchers and technical workers who are designing CRISPR genome editing experiments or will be analyzing genome editing data. The material is suitable both for experimentalists who want to learn more about data analysis as well as computational biologists who want to learn about genome editing design and analysis methods.
The requirements for this course are:
Working knowledge of CRISPR genome editing techniques, including genome-wide screens and tiling screens.
Also a working knowledge of basic laboratory processes such as PCR, next-generation sequencing, etc.
Some experience running simple commands on a terminal (Linux, Windows, or OSX)
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