Entering edit mode
4.8 years ago
Estbioq
•
0
I have done a LC-MS/MS analysis of the proteins of a gram-positive bacterium. I need to differentiate the membrane proteins from the others, but i only have the accession number. Do you know how I can know the subcellular location of each of the thousand proteins that I have?
1) Look at this paper below.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582598/pdf/1471-2105-13-290.pdf
it's for multi-label proteins, but it enumerates a lot of other tools.
2)
https://www.researchgate.net/post/Is_anybody_familiar_with_subcellular_location_of_proteins
The approach above is limited to Uniprot-proteins. But you have UniProtKB accession numbers,
don't you? - it may help you.
Can you post a few example accession #?