Job:Need help read-in the methylation raw datasets with .idat and .txt files

Question

[isabella.jyhou]

Hi all,

My name is Isabella, I am a researcher at a university in the United States. We are currently doing a DNA methylation related project, and we found a dataset that was pretty interesting to us.

The paper is written by Bormann et.al, “Reduced DNA methylation patterning and transcriptional connectivity define human skin aging”, and the dataset can be publicly accessed on https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-4385/. However, the datasets uploaded to EMBL were the raw datasets with .idat and .txt files, and we unfortunately dont have the capibility to convert them to the datasets with \beta value.

We wonder if anyone can help us read-in the datasets, match the raw data with clinical info, and calculate the \beta value. We can pay on hourly base.

Please contact me at [e-mail], if interested.

Thanks,
Isabella

[ATpoint]

Providing an email address will give you plethora of spam, hope you realize this.

[Benn]

Maybe follow the link in the comment from genomax:

https://genohub.com/bioinformatics-services-and-providers/