I would like to use 23andMe to get some raw data out of my genome.
23andMe sends the samples to LabCorp which uses Illumina OmniExpress Plus Genotyping BeadChip.
I don't know much about this technology and am much more familiar with the Illumina GA II sequencer and recently completed training for the HiSeq 2000. I assume that the BeadChip genotype information can be converted into a partially incomplete genomic sequence. Indels and transposons would not be detectable but SNPs would show up.
What percentage of the human genome can this technology cover?
For me the preferable definition of "covered" is:
The number of letters determined (above some accuracy threshold) divided by 2.9 billion.
- Can the technology multiplex multiple individuals into one run?
- How much do supplies cost to do one run?