I'm trying to deal with histone mark and their localization on the genome. I read that marks H3K4me3 are localized in the promoter regions. But I know that promoters are free of nucleosomes. How is this possible? Do I understand correctly that the presence of histone marks from an experiment Chip-seq means the presence of a nucleosome in this region? I read several articles, but did not find the answer.
I will be glad to any answer, especially useful articles on this topic.