Question: Is there a LIST of available drugs and their target proteins to download?
3
gravatar for entropy
10 days ago by
entropy30
entropy30 wrote:

Is there a downloadable LIST of available drugs and their target proteins?

For example like this:

Protein Drug

--------- ---------

CXCR4 Ibalizumab

Protein2 Drug2

and so on

It may also include not approved drugs.

I have a large list of targets and want to see "programmatically" which of them has already drug molecules available?

If possible, no commercial limitation as well.

thank you

ADD COMMENTlink modified 10 days ago by Kevin Blighe48k • written 10 days ago by entropy30
3
gravatar for Jean-Karim Heriche
10 days ago by
EMBL Heidelberg, Germany
Jean-Karim Heriche20k wrote:

This is available in DrugBank. You need to register to be able to download data.

ADD COMMENTlink written 10 days ago by Jean-Karim Heriche20k

Thanks. I got the impression that there is limitation for commercial usage of it? Is there not any other source with no limitations?

ADD REPLYlink written 10 days ago by entropy30
2
gravatar for Eric Lim
10 days ago by
Eric Lim1.4k
Stoke Therapeutics, Inc
Eric Lim1.4k wrote:

You can try https://www.targetvalidation.org, which essentially uses ChEMBL but with nicer interface and API.

For example, https://www.targetvalidation.org/evidence/ENSG00000121966/EFO_1000068?view=sec:known_drug

I don't know their licensing structure.

ADD COMMENTlink modified 10 days ago • written 10 days ago by Eric Lim1.4k
2
gravatar for Kevin Blighe
10 days ago by
Kevin Blighe48k
Kevin Blighe48k wrote:

Off the top of my head, ones to search include:

Not all of these may be exactly what you need.

Another one:

Kevin

ADD COMMENTlink modified 7 days ago • written 10 days ago by Kevin Blighe48k
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