Question: Is there a LIST of available drugs and their target proteins to download?
3
gravatar for entropy
5 months ago by
entropy40
entropy40 wrote:

Is there a downloadable LIST of available drugs and their target proteins?

For example like this:

Protein Drug

--------- ---------

CXCR4 Ibalizumab

Protein2 Drug2

and so on

It may also include not approved drugs.

I have a large list of targets and want to see "programmatically" which of them has already drug molecules available?

If possible, no commercial limitation as well.

thank you

ADD COMMENTlink modified 5 months ago by Kevin Blighe54k • written 5 months ago by entropy40
3
gravatar for Jean-Karim Heriche
5 months ago by
EMBL Heidelberg, Germany
Jean-Karim Heriche21k wrote:

This is available in DrugBank. You need to register to be able to download data.

ADD COMMENTlink written 5 months ago by Jean-Karim Heriche21k

Thanks. I got the impression that there is limitation for commercial usage of it? Is there not any other source with no limitations?

ADD REPLYlink written 5 months ago by entropy40
2
gravatar for Eric Lim
5 months ago by
Eric Lim1.6k
Stoke Therapeutics, Inc
Eric Lim1.6k wrote:

You can try https://www.targetvalidation.org, which essentially uses ChEMBL but with nicer interface and API.

For example, https://www.targetvalidation.org/evidence/ENSG00000121966/EFO_1000068?view=sec:known_drug

I don't know their licensing structure.

ADD COMMENTlink modified 5 months ago • written 5 months ago by Eric Lim1.6k
2
gravatar for Kevin Blighe
5 months ago by
Kevin Blighe54k
Kevin Blighe54k wrote:

Off the top of my head, ones to search include:

Not all of these may be exactly what you need.

Another one:

Kevin

ADD COMMENTlink modified 5 months ago • written 5 months ago by Kevin Blighe54k
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