Question: Limitation of UKBB genotyping/sequencing data in drug target identificantion
0
gravatar for Shicheng Guo
11 months ago by
Shicheng Guo8.5k
Shicheng Guo8.5k wrote:

Hi All,

We know that UKBB is very useful, free-available, exciting and amazing genetic data for population genetics, epidemiology, and genetic evolution. I want to know the limitation of this data, especially in drug target identification.

Thanks.

genotyping ukbb exome • 212 views
ADD COMMENTlink modified 11 months ago by rbagnall1.7k • written 11 months ago by Shicheng Guo8.5k
2
gravatar for rbagnall
11 months ago by
rbagnall1.7k
Australia
rbagnall1.7k wrote:

From the UK biobank "The UK Biobank 50k WES FE dataset is incorrectly mapped in a non-alt-aware manner."

See the paper describing the issue here (BioRxiv)

Download the pdf comment/response from the UK Biobank here

ADD COMMENTlink written 11 months ago by rbagnall1.7k

Thanks. I noticed this problem several days ago. Is there any other limitation?

ADD REPLYlink written 11 months ago by Shicheng Guo8.5k
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