Theoretical question regarding trancriptomics
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15 months ago
K.Gee ▴ 40

Hello. I was wondering what kind of information can I obtain if I have transcriptome data and the Dna genome sequence? I'm talking on theoretical bases. I know for a fact that I can start mapping the reads to the genome and start counting the number mapping reads, but after that?

Thank you in advance!

RNA-Seq transcriptomics sequence genome • 230 views
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It may be important to specify that you work with viral genomes.

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You have a strong memory. :-) I know that I hit the forum with many questions, but I'm still exploring the "world" of bioinformatics. To be fair, my question was on theoretical bases. I made it because I was looking to get a response from the experts to specify some definitions and strategics in mind. That's why I didn't mention the viruses. But still, if you have any information or any suggested paper specific on viruses, it will be appreciated.

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This can be dozens of different things, starting from finding mutations, expression analysis, copy number changes, sample classification based on similarities with other samples, co-expression networks and so on. Sounds like you are looking for a project?

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Thanks for the answer. Not precisely. I'm studying by making genomic comparisons, and I am trying to understand some definitions and clarify differences between other bioinformatician fields. So that's why I made the answer.

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