Effect Allele Frequency (EAF) to Minor Allele Frequency (MAF)
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20 months ago
bigfoot ▴ 10

How could I convert the Effect Allele Frequency (EAF) to Minor Allele Frequency (MAF) in GWAS summary statistics?

gwas maf genomics genome-wide genetics • 2.6k views
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20 months ago

Hello and good evening or morning, depending on your location.

First, please define [and understand] what is the 'effect allele' - it may already be the minor allele. Also, please read my previous answer, here: A: Definition of minor and major allele and connection with risk, effect, wildtype

Kevin

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