Question: Mitochondrial Genome In Chip-Seq?
1
gravatar for Ian
10.1 years ago by
Ian5.7k
University of Manchester, UK
Ian5.7k wrote:

Do people include the mitochondrial genome (chrM) in ChIP-seq analyses? At the mapping and peak calling stages.

mitochondria chip-seq • 3.2k views
ADD COMMENTlink written 10.1 years ago by Ian5.7k
3
gravatar for User 59
10.1 years ago by
User 5913k
User 5913k wrote:

Well if you're not expecting to pull down chrM sequences, they could well be used as as good measure of background noise (due to the experimental procedure, rather than non-specific binding of whatever TF you have used). This paper might be of interest to you as it specifically discusses the contribution of chrM mapped sequences on a publicly available ChIP-Seq experiment.

ADD COMMENTlink written 10.1 years ago by User 5913k
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