Meaning of the annotations of CDS for NCBI virus
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15 months ago
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Hi all,

in some references of NCBI, for example Sars-cov-2: https://www.ncbi.nlm.nih.gov/nuccore/NC_045512

some CDS are represented as: join(266..13468,13468..21555)

What does it means? The product is a protein where the it looks like the nucleotide at position 13468 has been used twice. How is the correct interpretation?

virus ncbi annotations • 388 views
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That particular annotation also includes following information:

join(266..13468,13468..21555)
/gene="ORF1ab"
/locus_tag="GU280_gp01"
/ribosomal_slippage
/note="pp1ab; translated by -1 ribosomal frameshift"


You can see the protein complement of SARS-CoV-2 virus in this table. This is probably a bit of a moving target since we are still understanding all things that this virus is capable of doing including its genome.

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To add the site join(266..13468,13468..21555) has a note /note="pp1ab; translated by -1 ribosomal frameshift"